Juan G?rtner的作品
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Nuclear pore. Nuclear pore complexes allow the transport of molecules across the nuclear envelope.
Exportin-5/RanGTP/miRNA-complex
激活胰高血糖素樣肽-1（GLP-1）受體的替爾泊肽（Mounjaro）肽
Major histocompatibility complex proteins (MHC) I and II on the surface of a dendritic cell
The GLP-receptor agonist tirzepatide (Mounjaro) before binding and bound to the receptor
Organoid tissue. An organoid is a miniaturized and simplified version of an organ produced in vitro.
外泌體，橫截面顯示蛋白質和 mRNA
The vascular endothelial growth factor (VEGF) promotes blood vessel formation (angiogenesis)
Growing tumor, angiogenic switch and neovascularization induced by VEGF-A
The pore forming toxin alpha-hemolysin from Staphylococcus aureus (side view)
Double-stranded circular RNA
The pore forming toxin alpha-hemolysin from Staphylococcus aureus (side and top view)
Growing tumor, angiogenic switch and neovascularization
Enzymes involved in microRNA processing: exportin/RanGTP(light blue)) dicer/TRP, Argonaute (top right). pre-microRNA and microRNA (red)
Enzymes involved in microRNA processing: exportin/RanGTP(left)) dicer/TRP, Argonaute (right). pre-microRNA and microRNA (red)
Exosomes, cross section showing proteins and mRNA
鈉-葡萄糖協同轉運蛋白 2（SGLT2）與抑制劑復合物，可降低血糖水平
囊性纖維化跨膜傳導調節因子，CFTR關閉（左）和結合ATP（紅色）的開放形式
Epigenetics: DNA methylation by the DNA methyl transferase I (DMNT1)
表皮生長因子受體的非活性（左）和活性（右）形式
一種新的抗生素（zosurabalpin）在鮑氏不動桿菌的膜間轉運蛋白中捕獲脂多糖
G 蛋白偶聯受體：視紫紅質（左）和 T 細胞、多巴胺和 GABA B 受體
癌基因：DNA 突變導致 KRAS 蛋白突變
處于高級囊胚階段的人類胚胎，剖面圖
阿爾茨海默病的免疫療法。抗體與β-淀粉樣蛋白纖維結合。
Transcription and translation: from DNA to a protein
GLP-1 受體，非活性形式（左）和與激動劑（司美格魯肽）和 G 蛋白的活性復合物
路易體神經元
HER3 (inactive conformation), a key receptor in cancer immunotherapy
低密度脂蛋白顆粒
脂肪組織中的脂肪細胞
Chimeric antigen receptor (CAR) therapy: Engineered T-cell attacks a leukemia cell
Dendritic cells detect a growing tumor
路易體的組成成分
免疫檢查點：T 細胞上的 PD-1（藍色）和癌細胞上的 PD-L1（紅色）之間的相互作用抑制 T 細胞
G protein-coupled receptors: rhodopsin (left) and the T-cell, dopamine and GABA B receptors
26S 蛋白酶體。蛋白酶體降解不需要或受損的蛋白質
人血清白蛋白分子
人類細胞分離外泌體。外泌體是細胞外囊泡，參與諸如凝血、廢物管理和細胞間通信等生理過程
淀粉樣β蛋白（左）及其錯誤折疊形式（右）。淀粉樣斑塊，阿爾茨海默病。
表觀遺傳學：DNA 甲基轉移酶 I（DMNT1）使 DNA 甲基化
The vascular endothelial growth factor receptor activated by VEGF. The activation leads to blood vessel formation.
克羅恩病 - 腸道疾病
骨髓中的多能干細胞
免疫檢查點抑制劑：治療性抗體阻斷 PD-1、CTLA-4 和 PD-1
抗原結合的 IgM 激活 C1 復合物
Calmodulin, a crucial messenger protein
關鍵腦受體：NMDA、AMPA 和 GABA 受體及其神經遞質
B 細胞受體二聚體結合抗原
A new antibiotic (zosurabalpin) traps lipopolysaccharide in the intermembrane transporter of Acinetobacter baylyi
GLP-1 受體，失活并被激動劑（司美格魯肽，紅色）和 G 蛋白包圍
Somatostatin about to bind to the somatostatin receptor
結合 4 種配體類似物的辣椒素受體 TRPV1。TRPV1 是一種感知熱量、調節體溫并導致疼痛感覺的離子通道。來源：PDB 條目 5is0。
Activation of the GABA B receptor by an agonist leads to a cAMP signal cascade
嵌合抗原受體（CAR）療法：工程 T 細胞攻擊白血病細胞
Chimeric antigen receptor (CAR) therapy: Engineered receptor on a T-cell binds to CD19-antigen on a leukemia cell
let7-precursor-microRNA (50 nucleotides) and let7 microRNA (21 nucleotides), a tumor suppressor
let7-precursor-microRNA in stick and surface depiction style, a tumor suppressor
The tumor suppressor let7-precursor-microRNA
RNA hairpin structure in stick and surface style. Pre-microRNAs and tRNAs contain RNA hairpin loops.
RNA hairpin structure. Pre-microRNAs and tRNAs contain RNA hairpin loops.
mRNA entering the cytosol through a nuclear pore
Exportin-5/RanGTP-complex transports miRNA through a nucleopore into the cytosol
Exportin-5(blue)/RanGTP(light violet)-complex transports miRNA (red) through nucleopores into the cytosol.
Exportin-5/RanGTP-complex transports miRNA through a nucleopore into the cytosol
Glucose about to bind to the sweet taste receptor
RNA hairpin structure
T-cell receptors and CD8 and CD4 co-receptors on a killer and a helper T-cell
Structure of a nuclear pore. The cytosol is on top. mRNA molecules (red) and proteins are visible in the nucleus
mRNA entering the cytosol through a nuclear pore
T-cell receptors and CD8 and CD4 co-receptors on a killer and a helper T-cell
Major histocompatibility complex proteins (MHC) I and II on the surface of a dendritic cell. Left MHC I, right MCH II. MHCII presents generally longer antigenic peptides (red) than MHC I.
Argonaute protein complexed with double stranded microRNA. Guide miRNA strand in red.
The dicer enzyme (blue) in complex with TRBP (violet) and precursor-microRNA (red). Dicer processes pre-microRNA to microRNA
The dicer enzyme (blue) in complex with TRBP (violet) and precursor-microRNA (red). Dicer processes pre-microRNA to microRNA
RNA 聚合酶 II 將 DNA 轉錄為 RNA
Ca2+/鈣調蛋白依賴性蛋白激酶 II 全酶
Activation of the NLRP3 inflammasome leads to pro-inflammatory cytokine secretion and pyroptosis
The NLRP3 inflammasome (hexamer)
表觀遺傳學：DOT1L 甲基化泛素化核小體的組蛋白
PETase 酶將 PET 分子分解為單體構件。PETase 是一種具有塑料回收潛力的細菌酶。
抗原結合的 IgM 激活 C1 復合物。補體激活的經典途徑。
A microglia cell. It plays an important role in the pathogenesis of Alzheimer's disease
細胞因子風暴、巨噬細胞和 T 效應細胞分離細胞因子
Activation of rhodopsin by light leads to the hyperpolarization of photoreceptor cells
CAR-T 療法：嵌合抗原受體識別白血病細胞
MDM2 PRoteine binden an dem p53 tumor suppressor und deaktivieren es.
分裂的癌細胞
腸道腫瘤
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